Dietary Restriction during Development Enlarges Intestinal and Hypodermal Lipid Droplets in Caenorhabditis elegans
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منابع مشابه
Dietary Restriction during Development Enlarges Intestinal and Hypodermal Lipid Droplets in Caenorhabditis elegans
Dietary restriction (DR) extends lifespan in man species and modulates evolutionary conserved signalling and metabolic pathways. Most of these studies were done in adult animals. Here we investigated fat phenotypes of C. elegans larvae and adults which were exposed to DR during development. This approach was named "developmental-DR" (dDR). Moderate as well as stringent dDR increased the triglyc...
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The nematode Caenorhabditis elegans has proved to be an excellent model organism for the study of development and aging. Many aging mutants have been discovered in the past two decades, and much has been discovered about the physiology of long-lived mutants. It therefore seems surprising that dietary restriction (DR) has not been extensively studied using C. elegans. The main reason for this is...
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[This corrects the article DOI: 10.1371/journal.pgen.1006135.].
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0046198